Osteochondrosis, Canine
Osteochondrosis, osteochondritis dissecans (OCD)
Dogs, humans, pigs, horses, cattle, chickens, and turkeys.
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Osteochondrosis is a disease that affects cartilage formation; the cartilage, due to an abnormal thickening, is unable to receive a normal supply of nutrients from the joint fluid, causing it to become weaker and more susceptible to damage. Cartilage provides a protective gliding layer between the bones in a joint, and when it is injured and lesions form, the dog will experience pain, lameness, and arthritis. Lesions may occur on one or both sides of the body.

#1 Scapula
#2 Humerus
#3 Humeral head
#4 Floating artilage and bone
#5 Detachment site
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In all animals, osteochondrosis can affect many different joints, but in the dog, the most common sites of disease are the shoulder, elbow, stifle or knee joint, and tarsus or hock. Generally, osteochondrosis occurs in young, large to giant breeds, although it is also seen in mixed breeds. The most commonly affected breeds include the German shepherd, golden and Labrador retriever, rottweiler, Great Dane, Bernese mountain dog, and Saint Bernard.
Lameness, pain, crepitus, and swelling of the affected joint(s).
Lameness and pain.
Osteochondrosis, or OCD, is a disease of cartilage formation that results in weakened cartilage. Because cartilage is the contact layer between bones forming a joint, joint pain, lameness, and progressive arthritis result when the cartilage is damaged. A form of the disease called osteochondritis dissecans (OCD) occurs when a weakened layer of cartilage forms a flap that becomes elevated because of joint fluid dissecting between it and the surrounding cartilage and bone. Mineralization can occur when the flap breaks off and floats around in the joint. This complication, called a joint mouse, can result in a “pebble-in-the-shoe” feeling of irritation for the dog, as well as intermittent or persistent lameness.
Osteochondrosis can affect any joint, but generally, there are four commonly affected joints in the dog:
The veterinarian may presume a diagnosis of osteochondrosis if the dog shows signs of disease and is a commonly affected breed. A definitive diagnosis requires analysis of x-rays.
The prognosis for shoulder osteochondrosis is excellent. Dogs with this disease often become normal after surgery, unless the lesion has been long-standing and arthritis has set in. The prognosis for elbow osteochondrosis is good but becomes guarded if significant arthritis is present. The prognosis for stifle osteochondrosis is good unless the lesion is very large or significant arthritis is present. The prognosis for tarsal or hock osteochondrosis is guarded because most of the dogs with this form of the disease already have significant arthritis. If the arthritis is severe, surgery may be no more effective than medical management.
The cause of osteochondrosis is unknown, but because the disease is primarily seen in large and giant breed dogs, a genetic component is suspected. Other factors, such as a high calorie diet, and diets that promote rapid growth, are also thought to be significant.
The treatment of osteochondrosis is surgical. A chondroplasty procedure, in which the cartilage is reshaped, involves opening up the affected joint to expose the lesion, removing the abnormal cartilage, and exposing the deeper blood vessels. Scar cartilage will fill in the defect, decreasing or eliminating the pain caused by the lesion.
Medical management of osteochondrosis consists of weight loss and non-steroidal anti-inflammatory medications, such as aspirin, carprofen, or etodolac.
Prevention generally includes avoiding calorie-dense diets in large to giant breed dogs. Puppies should be fed adult diets or giant breed growth formulations, and vitamin over-supplementation should be avoided. Maintaining a lean body condition also seems to decrease the risk of osteochondrosis.
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